Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2

To investigate the potential role of alcohol use disorder (AUD) in aging processes, we employed Levine’s epigenetic clock (DNAm PhenoAge) to estimate DNA methylation age in 331 individuals with AUD and 201 healthy controls (HC). We evaluated the effects of heavy, chronic alcohol consumption on epige...

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Detalles Bibliográficos
Autores principales: Luo, Audrey, Jung, Jeesun, Longley, Martha, Rosoff, Daniel B., Charlet, Katrin, Muench, Christine, Lee, Jisoo, Hodgkinson, Colin A., Goldman, David, Horvath, Steve, Kaminsky, Zachary A., Lohoff, Falk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901591/
https://www.ncbi.nlm.nih.gov/pubmed/31466081
http://dx.doi.org/10.1038/s41386-019-0500-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901591/
https://www.ncbi.nlm.nih.gov/pubmed/31466081
http://dx.doi.org/10.1038/s41386-019-0500-y

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