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More than one antibody of individual B cells revealed by single-cell immune profiling
Antibodies have a common structure consisting of two identical heavy (H) and two identical light (L) chains. It is widely accepted that a single mature B cell produces a single antibody through restricted synthesis of only one V(H)DJ(H) (encoding the H-chain variable region) and one V(L)J(L) (encodi...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901605/ https://www.ncbi.nlm.nih.gov/pubmed/31839985 http://dx.doi.org/10.1038/s41421-019-0137-3 |