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BMP2 Is Related to Hirschsprung’s Disease and Required for Enteric Nervous System Development

The enteric nervous system (ENS) is derived from neural crest cells (NCCs). Defects in ENS NCCs colonizing in the intestines lead to an absence of enteric ganglia in the colon and results in Hirschsprung’s disease (HSCR). Bone morphogenetic proteins (BMPs) play diverse roles in the proliferation, mi...

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Detalles Bibliográficos
Autores principales: Huang, Sizhou, Wang, Yi, Luo, Lingfei, Li, Xiaoqing, Jin, Xianqing, Li, Shuangshuang, Yu, Xiaoping, Yang, Min, Guo, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901830/
https://www.ncbi.nlm.nih.gov/pubmed/31849612
http://dx.doi.org/10.3389/fncel.2019.00523