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Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI

Nuclear receptors act as mediators of cancer-related inflammation and gene expression. They have a regulatory effect on genes encoding proteins related to drug adsorption, distribution, metabolism, and excretion. The aim of the present study was to highlight novel prognostic markers among polymorphi...

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Detalles Bibliográficos
Autores principales: De Mattia, Elena, Polesel, Jerry, Roncato, Rossana, Labriet, Adrien, Bignucolo, Alessia, Dreussi, Eva, Romanato, Loredana, Guardascione, Michela, Buonadonna, Angela, D'Andrea, Mario, Lévesque, Eric, Jonker, Derek, Couture, Félix, Guillemette, Chantal, Cecchin, Erika, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901926/
https://www.ncbi.nlm.nih.gov/pubmed/31850208
http://dx.doi.org/10.3389/fonc.2019.01312