Intranasal MMI-0100 Attenuates Aβ(1−42)- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway

Background: Accumulating evidence suggests inhibiting neuroinflammation as a potential target in therapeutic or preventive strategies for Alzheimer's disease (AD). MAPK-activated protein kinase II (MK2), downstream kinase of p38 mitogen activated protein kinase (MAPK) p38 MAPK, was unveiled as...

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Detalles Bibliográficos
Autores principales: Jiang, JinHong, Wang, Zhe, Liang, XueYa, Nie, YaoYan, Chang, Xin, Xue, HongXiang, Li, Shu, Min, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901946/
https://www.ncbi.nlm.nih.gov/pubmed/31849936
http://dx.doi.org/10.3389/fimmu.2019.02707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901946/
https://www.ncbi.nlm.nih.gov/pubmed/31849936
http://dx.doi.org/10.3389/fimmu.2019.02707

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