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Intranasal MMI-0100 Attenuates Aβ(1−42)- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway
Background: Accumulating evidence suggests inhibiting neuroinflammation as a potential target in therapeutic or preventive strategies for Alzheimer's disease (AD). MAPK-activated protein kinase II (MK2), downstream kinase of p38 mitogen activated protein kinase (MAPK) p38 MAPK, was unveiled as...
Autores principales: | Jiang, JinHong, Wang, Zhe, Liang, XueYa, Nie, YaoYan, Chang, Xin, Xue, HongXiang, Li, Shu, Min, Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901946/ https://www.ncbi.nlm.nih.gov/pubmed/31849936 http://dx.doi.org/10.3389/fimmu.2019.02707 |
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