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Insulin Signaling as a Key Moderator in Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is an autosomal dominant genetic disease characterized by multi-system involvement. Affected organ system includes skeletal muscle, heart, gastro-intestinal system and the brain. In this review, we evaluate the evidence for alterations in insulin signaling and their r...

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Detalles Bibliográficos
Autores principales: Nieuwenhuis, Sylvia, Okkersen, Kees, Widomska, Joanna, Blom, Paul, 't Hoen, Peter A. C., van Engelen, Baziel, Glennon, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901991/
https://www.ncbi.nlm.nih.gov/pubmed/31849810
http://dx.doi.org/10.3389/fneur.2019.01229