Cargando…

Insulin Signaling as a Key Moderator in Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is an autosomal dominant genetic disease characterized by multi-system involvement. Affected organ system includes skeletal muscle, heart, gastro-intestinal system and the brain. In this review, we evaluate the evidence for alterations in insulin signaling and their r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nieuwenhuis, Sylvia, Okkersen, Kees, Widomska, Joanna, Blom, Paul, 't Hoen, Peter A. C., van Engelen, Baziel, Glennon, Jeffrey C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901991/ https://www.ncbi.nlm.nih.gov/pubmed/31849810 http://dx.doi.org/10.3389/fneur.2019.01229

Ejemplares similares

Blood Transcriptome Profiling Links Immunity to Disease Severity in Myotonic Dystrophy Type 1 (DM1)
por: Nieuwenhuis, Sylvia, et al.
Publicado: (2022)

Clinical Outcome Evaluations and CBT Response Prediction in Myotonic Dystrophy
por: van As, Daniël, et al.
Publicado: (2021)

Structural white matter networks in myotonic dystrophy type 1
por: van Dorst, Maud, et al.
Publicado: (2018)

Human brain pathology in myotonic dystrophy type 1: A systematic review
por: Weijs, Ralf, et al.
Publicado: (2021)

Genetic determinants of disease severity in the myotonic dystrophy type 1 OPTIMISTIC cohort
por: Cumming, Sarah A., et al.
Publicado: (2019)

Associations Between Variant Repeat Interruptions and Clinical Outcomes in Myotonic Dystrophy Type 1
por: Wenninger, Stephan, et al.
Publicado: (2021)

Myotonic Dystrophy—A Progeroid Disease?
por: Meinke, Peter, et al.
Publicado: (2018)

Modeling of Myotonic Dystrophy Cardiac Phenotypes in Drosophila
por: Chakraborty, Mouli, et al.
Publicado: (2018)

Current Progress in CNS Imaging of Myotonic Dystrophy
por: Minnerop, Martina, et al.
Publicado: (2018)

TNNT2 Missplicing in Skeletal Muscle as a Cardiac Biomarker in Myotonic Dystrophy Type 1 but Not in Myotonic Dystrophy Type 2
por: Bosè, Francesca, et al.
Publicado: (2019)

Commentary: Autoimmune diseases in patients with myotonic dystrophy type 2
por: Damen, Manon J., et al.
Publicado: (2022)

Autoimmune Diseases in Patients With Myotonic Dystrophy Type 2
por: Peric, Stojan, et al.
Publicado: (2022)

High disease impact of myotonic dystrophy type 2 on physical and mental functioning
por: Tieleman, Alide A., et al.
Publicado: (2011)

Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1
por: van der Plas, Ellen, et al.
Publicado: (2022)

Of Mice and Men: Advances in the Understanding of Neuromuscular Aspects of Myotonic Dystrophy
por: Braz, Sandra O., et al.
Publicado: (2018)

Editorial: Beyond Borders: Myotonic Dystrophies–A European Perception
por: Schoser, Benedikt, et al.
Publicado: (2018)

Editorial: Myotonic Dystrophies: Developments in Research From Bench to Bedside
por: Silvestri, Gabriella, et al.
Publicado: (2020)

Validation of Motor Outcome Measures in Myotonic Dystrophy Type 2
por: Montagnese, Federica, et al.
Publicado: (2020)

Sleep Disorders in Four Patients With Myotonic Dystrophy Type 1
por: Urata, Yuka, et al.
Publicado: (2020)

Multisystemic Impairments in 93 Chinese Patients With Myotonic Dystrophy Type 1
por: Li, Mao, et al.
Publicado: (2020)

Overweight Is an Independent Risk Factor for Reduced Lung Volumes in Myotonic Dystrophy Type 1
por: Seijger, Charlotte G. W., et al.
Publicado: (2016)

An evaluation of 24 h Holter monitoring in patients with myotonic dystrophy type 1
por: Joosten, Isis B T, et al.
Publicado: (2022)

Cognitive behaviour therapy plus aerobic exercise training to increase activity in patients with myotonic dystrophy type 1 (DM1) compared to usual care (OPTIMISTIC): study protocol for randomised controlled trial
por: van Engelen, Baziel
Publicado: (2015)

Electrocardiographic predictors of infrahissian conduction disturbances in myotonic dystrophy type 1
por: Joosten, Isis B T, et al.
Publicado: (2020)

Neuropsychological and Psychological Functioning Aspects in Myotonic Dystrophy Type 1 Patients in Italy
por: Callus, Edward, et al.
Publicado: (2018)

Rare Disease: Cardiac Risk Assessment With MRI in Patients With Myotonic Dystrophy Type 1
por: Alì, Marco, et al.
Publicado: (2020)

Factors Influencing the Severity and Progression of Respiratory Muscle Dysfunction in Myotonic Dystrophy Type 1
por: Hartog, Leigh, et al.
Publicado: (2021)

Health-Related Quality of Life in Patients with Adult-Onset Myotonic Dystrophy Type 1: A Systematic Review
por: Landfeldt, Erik, et al.
Publicado: (2019)

Myotonic dystrophy type 1: A comparison between the adult‐ and late‐onset subtype
por: Joosten, Isis B.T., et al.
Publicado: (2022)

Living with myotonic dystrophy; what can be learned from couples? a qualitative study
por: Cup, Edith HC, et al.
Publicado: (2011)

Best practice guidelines and recommendations on the molecular diagnosis of myotonic dystrophy types 1 and 2
por: Kamsteeg, Erik-Jan, et al.
Publicado: (2012)

Abnormal Cortical Thickness Is Associated With Deficits in Social Cognition in Patients With Myotonic Dystrophy Type 1
por: Serra, Laura, et al.
Publicado: (2020)

Gray Matter Abnormalities in Myotonic Dystrophy Type 1: A Voxel-Wise Meta-Analysis
por: Jiang, Qirui, et al.
Publicado: (2022)

Cell Membrane Integrity in Myotonic Dystrophy Type 1: Implications for Therapy
por: González-Barriga, Anchel, et al.
Publicado: (2015)

Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI
por: Heskamp, Linda, et al.
Publicado: (2019)

Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1
por: Miller, Jacob N., et al.
Publicado: (2021)

Myotonic dystrophy
por: Patterson, VH
Publicado: (1990)

Central Nervous System Involvement as Outcome Measure for Clinical Trials Efficacy in Myotonic Dystrophy Type 1
por: Simoncini, Costanza, et al.
Publicado: (2020)

Ultrasonography of abdominal muscles: Differential diagnosis of late-onset Pompe disease and myotonic dystrophy type 1
por: Hsieh, Pei-Chen, et al.
Publicado: (2022)

Functional Ambulation Profile (FAP) Score as a Potential Marker of Gait Analysis in Myotonic Dystrophy Type 1
por: Kim, Sunyoung, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t0r2n80uue1j4r8crjdhqgupjj