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Anisodamine Ameliorates Hyperkalemia during Crush Syndrome through Estradiol-Induced Enhancement of Insulin Sensitivity

Hyperkalemia is a major cause of on-site death in crush syndrome (CS), which is more severe and common in male victims. Anisodamine is a belladonna alkaloid and widely used in China for treatment of shock through activation of α7 nicotinic acetylcholine receptor (α7nAChR). The present work was desig...

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Detalles Bibliográficos
Autores principales: Yu, Jian-Guang, Fan, Bo-Shi, Guo, Jin-Min, Shen, Yun-Jie, Hu, Ye-Yan, Liu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902024/
https://www.ncbi.nlm.nih.gov/pubmed/31849684
http://dx.doi.org/10.3389/fphar.2019.01444