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Synthetic Phosphodiester‐Linked 4‐Amino‐4‐deoxy‐l‐arabinose Derivatives Demonstrate that ArnT is an Inverting Aminoarabinosyl Transferase

4‐Amino‐4‐deoxy‐l‐arabinopyranose (Ara4N) residues have been linked to antibiotic resistance due to reduction of the negative charge in the lipid A and core regions of the bacterial lipopolysaccharide (LPS). To study the enzymatic transfer of Ara4N onto lipid A, which is catalysed by the ArnT transf...

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Detalles Bibliográficos
Autores principales: Olagnon, Charlotte, Monjaras Feria, Julia, Grünwald‐Gruber, Clemens, Blaukopf, Markus, Valvano, Miguel A., Kosma, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902282/
https://www.ncbi.nlm.nih.gov/pubmed/31233657
http://dx.doi.org/10.1002/cbic.201900349