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Accuracy, robustness and scalability of dimensionality reduction methods for single-cell RNA-seq analysis
BACKGROUND: Dimensionality reduction is an indispensable analytic component for many areas of single-cell RNA sequencing (scRNA-seq) data analysis. Proper dimensionality reduction can allow for effective noise removal and facilitate many downstream analyses that include cell clustering and lineage r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902413/ https://www.ncbi.nlm.nih.gov/pubmed/31823809 http://dx.doi.org/10.1186/s13059-019-1898-6 |