Accuracy, robustness and scalability of dimensionality reduction methods for single-cell RNA-seq analysis

BACKGROUND: Dimensionality reduction is an indispensable analytic component for many areas of single-cell RNA sequencing (scRNA-seq) data analysis. Proper dimensionality reduction can allow for effective noise removal and facilitate many downstream analyses that include cell clustering and lineage r...

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Detalles Bibliográficos
Autores principales: Sun, Shiquan, Zhu, Jiaqiang, Ma, Ying, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902413/
https://www.ncbi.nlm.nih.gov/pubmed/31823809
http://dx.doi.org/10.1186/s13059-019-1898-6

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