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Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex

BACKGROUND: Astral microtubules emanating from the mitotic centrosomes play pivotal roles in defining cell division axis and tissue morphogenesis. Previous studies have demonstrated that human transforming acidic coiled-coil 3 (TACC3), the most conserved TACC family protein, regulates formation of a...

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Detalles Bibliográficos
Autores principales: Rajeev, Resmi, Singh, Puja, Asmita, Ananya, Anand, Ushma, Manna, Tapas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902513/
https://www.ncbi.nlm.nih.gov/pubmed/31823729
http://dx.doi.org/10.1186/s12860-019-0242-z