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Editorial focus: understanding off-target effects as the key to successful RNAi therapy
With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we witness the RNAi therapy field reaching a critical turning point, when further improvements in drug candidate design and delivery pipelines should enable fast delivery of novel life changing treatments to patients....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902517/ https://www.ncbi.nlm.nih.gov/pubmed/31867046 http://dx.doi.org/10.1186/s11658-019-0196-3 |