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Editorial focus: understanding off-target effects as the key to successful RNAi therapy

With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we witness the RNAi therapy field reaching a critical turning point, when further improvements in drug candidate design and delivery pipelines should enable fast delivery of novel life changing treatments to patients....

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Detalles Bibliográficos
Autores principales:	Bartoszewski, Rafal, Sikorski, Aleksander F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902517/ https://www.ncbi.nlm.nih.gov/pubmed/31867046 http://dx.doi.org/10.1186/s11658-019-0196-3

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