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Abiraterone and MDV3100 inhibits the proliferation and promotes the apoptosis of prostate cancer cells through mitophagy

BACKGROUND: Abiraterone and MDV3100 are two effective anticancer agents for prostate cancer, however, the mechanism of their downstream action remains undefined. METHODS: A dual fluorescent biosensor plasmid was transfected in LNCaP cells to measure mitophagy. The DNA of LNCaP cells was extracted an...

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Detalles Bibliográficos
Autores principales: Han, Jingli, Zhang, Junhua, Zhang, Wei, Zhang, Dalei, Li, Ying, Zhang, Jinsong, Zhang, Yaqun, Diao, Tongxiang, Cui, Luwei, Li, Wenqing, Xiao, Fei, Liu, Ming, Zou, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902535/
https://www.ncbi.nlm.nih.gov/pubmed/31827406
http://dx.doi.org/10.1186/s12935-019-1021-9