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Comprehensive longitudinal study of epigenetic mutations in aging

BACKGROUND: The role of DNA methylation in aging has been widely studied. However, epigenetic mutations, here defined as aberrant methylation levels compared to the distribution in a population, are less understood. Hence, we investigated longitudinal accumulation of epigenetic mutations, using 994...

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Detalles Bibliográficos
Autores principales: Wang, Yunzhang, Karlsson, Robert, Jylhävä, Juulia, Hedman, Åsa K., Almqvist, Catarina, Karlsson, Ida K., Pedersen, Nancy L., Almgren, Malin, Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902582/
https://www.ncbi.nlm.nih.gov/pubmed/31818313
http://dx.doi.org/10.1186/s13148-019-0788-9