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A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY)

BACKGROUND: Fresh frozen plasma (FFP) is the accepted standard treatment for clotting factor replacement in bleeding patients during or immediately after cardiac surgery. In the United Kingdom prothrombin complex concentrate (PCC) is not licensed in this setting, although it is being used in Europe...

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Detalles Bibliográficos
Autores principales: Green, Laura, Roberts, Neil, Cooper, Jackie, Field, Jane, Gill, Ravi, Klein, Andrew, Agarwal, Seema, Stanworth, Simon, Johnston, Atholl, Monk, Vivienne, O’Brien, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902595/
https://www.ncbi.nlm.nih.gov/pubmed/31815658
http://dx.doi.org/10.1186/s13063-019-3759-8