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TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination

BACKGROUND: Interleukin-22 (IL-22) belongs to the IL-10 cytokine family and is mainly produced by activated Th1 cells. Although IL-22 expression is reported to be elevated in many cancers, and increased IL-22 expression correlates with tumor progression and poor prognosis, little is known about the...

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Detalles Bibliográficos
Autores principales: Li, Wei, Li, Fen, Lei, Weiwei, Tao, Zezhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902597/
https://www.ncbi.nlm.nih.gov/pubmed/31823782
http://dx.doi.org/10.1186/s12964-019-0484-6