Extended treatment with MY-NEOVAX, personalized neoantigen-enhanced oncolytic viruses, for two end-stage cancer patients

Neoantigen vaccines involving multi-peptides and poly-epitope-encoding RNA or DNA have undergone early phase clinical testing with modest reported antitumor effects [ 1]. The less-than-expected activity of these neoantigenic vaccines may correspond with the development of immune escape mechanisms. O...

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Detalles Bibliográficos
Autores principales: Bouvet, Michael, Reid, Tony R, Larson, Chris, Oronsky, Bryan, Carter, Corey, Morris, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902621/
https://www.ncbi.nlm.nih.gov/pubmed/31844525
http://dx.doi.org/10.1093/omcr/omz105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902621/
https://www.ncbi.nlm.nih.gov/pubmed/31844525
http://dx.doi.org/10.1093/omcr/omz105

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