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AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

AMPK is a central regulator of energy homeostasis. AMPK not only elicits acute metabolic responses but also promotes metabolic reprogramming and adaptations in the long-term through regulation of specific transcription factors and coactivators. We performed a whole-genome transcriptome profiling in...

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Detalles Bibliográficos
Autores principales: Collodet, Caterina, Foretz, Marc, Deak, Maria, Bultot, Laurent, Metairon, Sylviane, Viollet, Benoit, Lefebvre, Gregory, Raymond, Frederic, Parisi, Alice, Civiletto, Gabriele, Gut, Philipp, Descombes, Patrick, Sakamoto, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902666/
https://www.ncbi.nlm.nih.gov/pubmed/31404503
http://dx.doi.org/10.1096/fj.201900841R