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miR-195-Sirt3 Axis Regulates Angiotensin II-Induced Hippocampal Apoptosis and Learning Impairment in Mice

OBJECTIVE: Apoptosis plays an essential role in cell development and aging, which is associated with a series of diseases, such as neurodegeneration. MircoRNAs exert important roles in the regulation of gene expression. As a stress-responsive deacetylase in mitochondria, sirtuin-3 (sirt3) is a key r...

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Detalles Bibliográficos
Autores principales: Fan, Xiaosheng, Xiao, Ming, Zhang, Qinghai, Li, Na, Bu, Peili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902854/
https://www.ncbi.nlm.nih.gov/pubmed/31827339
http://dx.doi.org/10.2147/PRBM.S221209