Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea

A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed. The obtained spiro pseudothiohydantoin derivatives were fou...

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Detalles Bibliográficos
Autores principales: Kobelev, Aleksandr I, Tretyakov, Nikita A, Stepanova, Ekaterina E, Dmitriev, Maksim V, Rubin, Michael, Maslivets, Andrey N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902856/
https://www.ncbi.nlm.nih.gov/pubmed/31839832
http://dx.doi.org/10.3762/bjoc.15.280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902856/
https://www.ncbi.nlm.nih.gov/pubmed/31839832
http://dx.doi.org/10.3762/bjoc.15.280

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