Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis

The argyrins are secondary metabolites from myxobacteria with antibiotic activity against Pseudomonas aeruginosa. Studying their structure–activity relationship is hampered by the complexity of the chemical total synthesis. Mutasynthesis is a promising approach where simpler and fully synthetic inte...

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Detalles Bibliográficos
Autores principales: Siebert, David C B, Sommer, Roman, Pogorevc, Domen, Hoffmann, Michael, Wenzel, Silke C, Müller, Rolf, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902895/
https://www.ncbi.nlm.nih.gov/pubmed/31839838
http://dx.doi.org/10.3762/bjoc.15.286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902895/
https://www.ncbi.nlm.nih.gov/pubmed/31839838
http://dx.doi.org/10.3762/bjoc.15.286

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