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Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function

Podocytes are key cells in maintaining the integrity of the glomerular filtration barrier and preventing albuminuria. Glycogen synthase kinase 3 (GSK3) is a multi‐functional serine/threonine kinase existing as two distinct but related isoforms (α and β). In the podocyte it has previously been report...

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Detalles Bibliográficos
Autores principales: Hurcombe, Jennifer A., Lay, Abigail C., Ni, Lan, Barrington, Alexandra F., Woodgett, Jim R., Quaggin, Susan E., Welsh, Gavin I., Coward, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902909/
https://www.ncbi.nlm.nih.gov/pubmed/31825015
http://dx.doi.org/10.1096/fba.2019-00011