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Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function
Podocytes are key cells in maintaining the integrity of the glomerular filtration barrier and preventing albuminuria. Glycogen synthase kinase 3 (GSK3) is a multi‐functional serine/threonine kinase existing as two distinct but related isoforms (α and β). In the podocyte it has previously been report...
Autores principales: | Hurcombe, Jennifer A., Lay, Abigail C., Ni, Lan, Barrington, Alexandra F., Woodgett, Jim R., Quaggin, Susan E., Welsh, Gavin I., Coward, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902909/ https://www.ncbi.nlm.nih.gov/pubmed/31825015 http://dx.doi.org/10.1096/fba.2019-00011 |
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