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Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart

Diabetes mellitus is often associated with cardiovascular complications, which is the leading cause of morbidity and mortality among patients with diabetes mellitus, but little is known about the mechanism that connects diabetes mellitus to the development of cardiovascular dysfunction. OBJECTIVE: W...

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Detalles Bibliográficos
Autores principales: Li, Huaping, Fan, Jiahui, Zhao, Yanru, Zhang, Xiaorong, Dai, Beibei, Zhan, Jiabing, Yin, Zhongwei, Nie, Xiang, Fu, Xiang-Dong, Chen, Chen, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903355/
https://www.ncbi.nlm.nih.gov/pubmed/31638474
http://dx.doi.org/10.1161/CIRCRESAHA.119.314898