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Dynamical comparison between Drosha and Dicer reveals functional motion similarities and dissimilarities

Drosha and Dicer are RNase III family members of classes II and III, respectively, which play a major role in the maturation of micro-RNAs. The two proteins share similar domain arrangement and overall fold despite no apparent sequence homology. The overall structural and catalytic reaction similari...

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Detalles Bibliográficos
Autores principales: Aharoni, Rotem, Tobi, Dror
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903759/
https://www.ncbi.nlm.nih.gov/pubmed/31821368
http://dx.doi.org/10.1371/journal.pone.0226147