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Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer’s disease

BACKGROUND: Melanopsin-expressing retinal ganglion cells (mRGCs), intrinsically photosensitive RGCs, mediate the light-based pupil response and the light entrainment of the body’s circadian rhythms through their connection to the pretectal nucleus and hypothalamus, respectively. Increased awareness...

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Detalles Bibliográficos
Autores principales: Oh, Angela J., Amore, Giulia, Sultan, William, Asanad, Samuel, Park, Jason C., Romagnoli, Martina, La Morgia, Chiara, Karanjia, Rustum, Harrington, Michael G., Sadun, Alfredo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903762/
https://www.ncbi.nlm.nih.gov/pubmed/31821378
http://dx.doi.org/10.1371/journal.pone.0226197