Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain

A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thi...

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Detalles Bibliográficos
Autores principales: Naylor, Brooke, Hesam-Shariati, Negin, McAuley, James H., Boag, Simon, Newton-John, Toby, Rae, Caroline D., Gustin, Sylvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903775/
https://www.ncbi.nlm.nih.gov/pubmed/31849800
http://dx.doi.org/10.3389/fneur.2019.01110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903775/
https://www.ncbi.nlm.nih.gov/pubmed/31849800
http://dx.doi.org/10.3389/fneur.2019.01110

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