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Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules

Single-cell screens enable high-throughput functional assessment of enhancers in their endogenous genomic context. However, the design of current studies limits their application to identifying the primary gene targets of enhancers. Here, we improve the experimental and computational parameters of s...

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Detalles Bibliográficos
Autores principales: Xie, Shiqi, Armendariz, Daniel, Zhou, Pei, Duan, Jialei, Hon, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904118/
https://www.ncbi.nlm.nih.gov/pubmed/31775028
http://dx.doi.org/10.1016/j.celrep.2019.10.073