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Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus. While estrogens facilitate long-term potentiation (LTP), androgens are involved in the induction of long-term depression (LTD) and...

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Detalles Bibliográficos
Autores principales: Tozzi, Alessandro, Durante, Valentina, Manca, Paolo, Di Mauro, Michela, Blasi, Juan, Grassi, Silvarosa, Calabresi, Paolo, Kawato, Suguru, Pettorossi, Vito Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904272/
https://www.ncbi.nlm.nih.gov/pubmed/31866827
http://dx.doi.org/10.3389/fncel.2019.00534