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Sequestration of Late Antigens Within Viral Factories Impairs MVA Vector-Induced Protective Memory CTL Responses

Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after infection with Modified Vaccinia Virus Ankara (MVA). L...

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Detalles Bibliográficos
Autores principales: Tao, Sha, Tao, Ronny, Busch, Dirk H., Widera, Marek, Schaal, Heiner, Drexler, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904312/
https://www.ncbi.nlm.nih.gov/pubmed/31867011
http://dx.doi.org/10.3389/fimmu.2019.02850