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Endolysosomal Ca(2+) Signaling in Cancer: The Role of TPC2, From Tumorigenesis to Metastasis
Ca(2+) homeostasis is dysregulated in cancer cells and affects processes such as tumorigenesis, angiogenesis, autophagy, progression, and metastasis. Emerging evidence has suggested that endolysosomal cation channels sustain several cancer hallmarks involving proliferation, metastasis, and angiogene...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904370/ https://www.ncbi.nlm.nih.gov/pubmed/31867325 http://dx.doi.org/10.3389/fcell.2019.00302 |