Virtual clinical trials identify effective combination therapies in ovarian cancer

A major issue in oncology is the high failure rate of translating preclinical results in successful clinical trials. Using a virtual clinical trial simulations approach, we present a mathematical framework to estimate the added value of combinatorial treatments in ovarian cancer. This approach was a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kozłowska, Emilia, Vallius, Tuulia, Hynninen, Johanna, Hietanen, Sakari, Färkkilä, Anniina, Hautaniemi, Sampsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904444/
https://www.ncbi.nlm.nih.gov/pubmed/31822719
http://dx.doi.org/10.1038/s41598-019-55068-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904444/
https://www.ncbi.nlm.nih.gov/pubmed/31822719
http://dx.doi.org/10.1038/s41598-019-55068-z

Ejemplares similares