The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development

Human-specific gene duplications (HSGDs) have recently emerged as key modifiers of brain development and evolution. However, the molecular mechanisms underlying the function of HSGDs remain often poorly understood. In humans, a truncated duplication of SRGAP2A led to the emergence of two human-speci...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Ewoud R. E., Kupferman, Justine V., Stackmann, Michelle, Polleux, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904453/
https://www.ncbi.nlm.nih.gov/pubmed/31822692
http://dx.doi.org/10.1038/s41598-019-54887-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904453/
https://www.ncbi.nlm.nih.gov/pubmed/31822692
http://dx.doi.org/10.1038/s41598-019-54887-4

Ejemplares similares