Enteric neuronal cell therapy reverses architectural changes in a novel diphtheria toxin-mediated model of colonic aganglionosis

Hirschsprung disease (HSCR) is characterized by absence of the enteric nervous system (ENS) in the distal bowel. Despite removal of the aganglionic segment, gastrointestinal (GI) problems persist. Cell therapy offers potential treatment but use of genetic models is limited by their poor survival. We...

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Detalles Bibliográficos
Autores principales: Bhave, Sukhada, Arciero, Emily, Baker, Corey, Ho, Wing Lam, Stavely, Rhian, Goldstein, Allan M., Hotta, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904570/
https://www.ncbi.nlm.nih.gov/pubmed/31822721
http://dx.doi.org/10.1038/s41598-019-55128-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904570/
https://www.ncbi.nlm.nih.gov/pubmed/31822721
http://dx.doi.org/10.1038/s41598-019-55128-4

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