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A multi-genotype therapeutic human papillomavirus vaccine elicits potent T cell responses to conserved regions of early proteins

Despite an efficacious prophylactic human papillomavirus (HPV) vaccine there is still a considerable global burden of HPV-related disease. Therapeutic vaccines that could prevent cancers in at-risk women are urgently needed. Most candidate therapeutic vaccines have focused on two high-risk (hr) HPV...

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Detalles Bibliográficos
Autores principales: Hancock, Gemma, Blight, Joshua, Lopez-Camacho, Cesar, Kopycinski, Jakub, Pocock, Mamatha, Byrne, Wendy, Price, Michael J., Kemlo, Phillip, Evans, Ranoromanana Ionitiana, Bloss, Angela, Saunders, Kathryn, Kirton, Richard, Andersson, Monique, Hellner, Karin, Reyes-Sandoval, Arturo, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904585/
https://www.ncbi.nlm.nih.gov/pubmed/31822717
http://dx.doi.org/10.1038/s41598-019-55014-z