Intracellular delivery of therapeutic antibodies into specific cells using antibody-peptide fusions

Because of their favorable properties as macromolecular drugs, antibodies are a very successful therapeutic modality for interfering with disease-relevant targets in the extracellular space or at the cell membrane. However, a large number of diseases involve cytosolic targets and designing antibodie...

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Detalles Bibliográficos
Autores principales: Gaston, Julie, Maestrali, Nicolas, Lalle, Guilhem, Gagnaire, Marie, Masiero, Alessandro, Dumas, Bruno, Dabdoubi, Tarik, Radošević, Katarina, Berne, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904672/
https://www.ncbi.nlm.nih.gov/pubmed/31822703
http://dx.doi.org/10.1038/s41598-019-55091-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904672/
https://www.ncbi.nlm.nih.gov/pubmed/31822703
http://dx.doi.org/10.1038/s41598-019-55091-0

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