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Intracellular delivery of therapeutic antibodies into specific cells using antibody-peptide fusions
Because of their favorable properties as macromolecular drugs, antibodies are a very successful therapeutic modality for interfering with disease-relevant targets in the extracellular space or at the cell membrane. However, a large number of diseases involve cytosolic targets and designing antibodie...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904672/ https://www.ncbi.nlm.nih.gov/pubmed/31822703 http://dx.doi.org/10.1038/s41598-019-55091-0 |