Customisation and validation of a low-volume plasma renin activity immunoassay: Enabling of regulatory compliant determination in paediatric trials

OBJECTIVES: Investigations of plasma renin activity (PRA) in children are urgently required. Small-volume, regulatory guideline compliant, bioanalytical assays tailored for paediatric application could facilitate to overcome this hurdle. Ethical constraints given e.g. by the European Medicines Agenc...

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Detalles Bibliográficos
Autores principales: Suessenbach, F.K., Tins, J., Burckhardt, B.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904673/
https://www.ncbi.nlm.nih.gov/pubmed/31867426
http://dx.doi.org/10.1016/j.plabm.2019.e00144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904673/
https://www.ncbi.nlm.nih.gov/pubmed/31867426
http://dx.doi.org/10.1016/j.plabm.2019.e00144

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