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Selective Effects of Thioridazine on Self-Renewal of Basal-Like Breast Cancer Cells

Several recent publications demonstrated that DRD2-targeting antipsychotics such as thioridazine induce proliferation arrest and apoptosis in diverse cancer cell types including those derived from brain, lung, colon, and breast. While most studies show that 10–20 µM thioridazine leads to reduced pro...

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Detalles Bibliográficos
Autores principales: Tegowski, Matthew, Fan, Cheng, Baldwin, Albert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904738/
https://www.ncbi.nlm.nih.gov/pubmed/31822725
http://dx.doi.org/10.1038/s41598-019-55145-3