Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake

In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available exhibit several limitations, mainly related to drug toxicity and reduced efficacy in some regions. Miltefosine (MF), the only oral drug available for leishmaniasis treatment, is no...

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Detalles Bibliográficos
Autores principales: Espada, Caroline R., Magalhães, Rubens M., Cruz, Mario C., Machado, Paulo R., Schriefer, Albert, Carvalho, Edgar M., Hornillos, Valentín, Alves, João M., Cruz, Angela K., Coelho, Adriano C., Uliana, Silvia R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Includes articles from the special issue “Novel therapies for cutaneous leishmaniasis”, pp. 106 - 179
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904789/
https://www.ncbi.nlm.nih.gov/pubmed/30850347
http://dx.doi.org/10.1016/j.ijpddr.2019.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904789/
https://www.ncbi.nlm.nih.gov/pubmed/30850347
http://dx.doi.org/10.1016/j.ijpddr.2019.02.005

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