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Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming
Critically important to the maintenance of the glutathione (GSH) redox cycle are the activities of many selenocysteine-containing GSH metabolizing enzymes whose translation is controlled by the epitranscriptomic writer alkylation repair homolog 8 (ALKBH8). ALKBH8 is a tRNA methyltransferase that met...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832/ https://www.ncbi.nlm.nih.gov/pubmed/31765888 http://dx.doi.org/10.1016/j.redox.2019.101375 |