A Mechanosensitive Channel Governs Lipid Flippase-Mediated Echinocandin Resistance in Cryptococcus neoformans

Echinocandins show fungicidal activity against common invasive mycoses but are ineffective against cryptococcosis. The underlying mechanism for echinocandin resistance in Cryptococcus neoformans remains poorly understood but has been shown to involve Cdc50, the regulatory subunit of lipid flippase....

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Detalles Bibliográficos
Autores principales: Cao, Chengjun, Wang, Yina, Husain, Seema, Soteropoulos, Patricia, Xue, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904872/
https://www.ncbi.nlm.nih.gov/pubmed/31822582
http://dx.doi.org/10.1128/mBio.01952-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904872/
https://www.ncbi.nlm.nih.gov/pubmed/31822582
http://dx.doi.org/10.1128/mBio.01952-19

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