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Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy

Diseases where fibrosis plays a major role accounts for enormous morbidity and mortality and yet we have very little in our therapeutic arsenal despite decades of research and clinical trials. Our understanding of fibrosis biology is primarily built on data generated in conventional mono-culture or...

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Detalles Bibliográficos
Autores principales: Oakley, Fiona, Gee, Lucy M, Sheerin, Neil S, Borthwick, Lee A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904905/
https://www.ncbi.nlm.nih.gov/pubmed/31731225
http://dx.doi.org/10.1016/j.coph.2019.10.004