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1,25-(OH)(2)D(3)/Vitamin D receptor alleviates systemic lupus erythematosus by downregulating Skp2 and upregulating p27
BACKGROUND: Recent evidence has suggested that the 1,25(OH)(2)D(3)/Vitamin D receptor (VDR) acts to suppress the immune response associated with systemic lupus erythematosus (SLE), a serious multisystem autoimmune disease. Hence, the aim of the current study was to investigate the mechanism by which...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905035/ https://www.ncbi.nlm.nih.gov/pubmed/31823770 http://dx.doi.org/10.1186/s12964-019-0488-2 |