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Differential expression of glial cell line-derived neurotrophic factor splice variants in the mouse brain

Glial cell line-derived neurotrophic factor (GDNF) plays a critical role in neuronal survival and function. GDNF has two major splice variants in the brain, α-pro-GDNF and β-pro-GDNF, and both isoforms have strong neuroprotective effects on dopamine neurons. However, the expression of the GDNF splic...

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Detalles Bibliográficos
Autores principales: Gu, Xiao-He, Li, Heng, Zhang, Lin, He, Tao, Chai, Xiang, Wei, He, Gao, Dian-Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905338/
https://www.ncbi.nlm.nih.gov/pubmed/31552899
http://dx.doi.org/10.4103/1673-5374.265561