Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma

Abnormal circulation in solid tumors results in hypoxia, which modulates both tumor intrinsic malignant properties as well as anti-tumor immune responses. Given the importance of hypoxia in glioblastoma (GBM) biology and particularly in shaping anti-tumor immunity, we analyzed which immunomodulatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohapatra, Soumya R., Sadik, Ahmed, Tykocinski, Lars-Oliver, Dietze, Jørn, Poschet, Gernot, Heiland, Ines, Opitz, Christiane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905408/
https://www.ncbi.nlm.nih.gov/pubmed/31866995
http://dx.doi.org/10.3389/fimmu.2019.02762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905408/
https://www.ncbi.nlm.nih.gov/pubmed/31866995
http://dx.doi.org/10.3389/fimmu.2019.02762

Ejemplares similares