Prolonged ovarian storage of mature Drosophila oocytes dramatically increases meiotic spindle instability

Human oocytes frequently generate aneuploid embryos that subsequently miscarry. In contrast, Drosophila oocytes from outbred laboratory stocks develop fully regardless of maternal age. Since mature Drosophila oocytes are not extensively stored in the ovary under laboratory conditions like they are i...

Descripción completa

Detalles Bibliográficos
Autores principales: Greenblatt, Ethan J, Obniski, Rebecca, Mical, Claire, Spradling, Allan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905857/
https://www.ncbi.nlm.nih.gov/pubmed/31755866
http://dx.doi.org/10.7554/eLife.49455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905857/
https://www.ncbi.nlm.nih.gov/pubmed/31755866
http://dx.doi.org/10.7554/eLife.49455

Ejemplares similares